US NAS workshop raises issue of animal tests as ‘gold standard’

A recent US workshop on toxicity testing and decision making by the National Academy of Sciences (NAS) raised the concern of the efficacy of animal test methods.

“One of the things that we are finding is that we are having the most success in areas where human data exists to make those comparisons,” she added. As an example, she pointed to recent research suggesting that OECD test guidelines for skin sensitisation may give better predictions of human toxicity than the local lymph node assay (LLNA) in rodents.


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